She had additional imaging that showed, in addition to the palpable node, she had multiple left axillary nodes and more than one lesion in the lung itself, the largest being about 2 cm. She was sent on for additional evaluation that included a core needle biopsy of both the mass in the breast and axilla, confirming ER-positive and HER2-positive breast cancer. This is the case of a 49-year-old woman who was seen by her gynecologist for her routine physical and she had a full exam, fortunately, because they detected a palpable mass in her left breast and a 3 cm node in her axilla. William Gradishar, MD: This case builds on some of the things we were talking about in patients with relapsed HER2-positive disease and brain mets. Bill, would you go ahead and talk to us about your case? Thankfully, they’re living a long time so we do need options for these patients. We have a couple of cases to talk about, brain metastasis, which is a difficult problem in our practices for many patients.
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